There is also some crosstalk with the H 2 S signalling pathway and the nitric oxide pathway, since H 2 S can degrade the molecule known as S-nitrosoglutathione,  which serves as an intracellular (and to a degree, extracellular  ) reservoir of nitric oxide that garlic is known to stimulate.  Due to this, the influence of garlic on blood pressure and blood flow is in part due to nitric oxide signalling per se (the vasorelaxing effect of opening potassium channels to be discussed in the ion channels section  ) and in part an influence of the hydrogen sulfide system unto the nitric oxide system.
Androgens are responsible for the growth spurt of adolescence and for the eventual termination of linear growth, which is brought about by fusion of the epiphyseal growth centers. In children, exogenous androgens accelerate linear growth rates but may cause a disproportionate advancement in bone maturation. Use over long periods may result in fusion of the epiphyseal growth centers and termination of growth process. Androgens have been reported to stimulate the production of red blood cells by enhancing the production of erythropoeitic stimulating factor. During exogenous administration of androgens,Â endogenous testosterone Â release is inhibited through feedback inhibition of pituitary luteinizing hormone (LH).