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Noxious input to the spinal cord is known to produce central sensitization, which consists of allodynia , exaggeration of pain, and punctuate hyperalgesia , extreme sensitivity to pain. Two types of mechanical hyperalgesia can occur: 1) touch that is normally painless in the uninjured surroundings of a cut or tear can trigger painful sensations (touch-evoked hyperalgesia), and 2) a slightly painful pin prick stimulation is perceived as more painful around a focused area of inflammation (punctuate hyperalgesia). Touch-evoked hyperalgesia requires continuous firing of primary afferent nociceptors, and punctuate hyperalgesia does not require continuous firing which means it can persist for hours after a trauma and can be stronger than normally experienced. In addition, it was found that patients with neuropathic pain, histamine ionophoresis resulted in a sensation of burning pain rather than itch, which would be induced in normal healthy patients. This shows that there is spinal hypersensitivity to C-fiber input in chronic pain. [2]

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The foods that bring on a gallbladder attack vary with each individual. Some foods seem to be fine with some individuals and cause problems with others. By keeping a food diary of what you eat and symptoms you experience, you can narrow down which foods seem to cause you the most problems and avoid them. For example, many people tolerate tap water, poached eggs and fowl with the skin removed. Some people can tolerate small amounts of the foods to avoid. Often doctors may offer contradictory information and sometimes you see the same foods on lists of what not to eat and what to eat. So to some degree, you have to determine what is specifically causing you problems in order to identify which foods you can eat while you have gallstones.

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